Italy's two great art cities, linked by a fast train. Spend four nights in Rome for the Colosseum, the Vatican Museums and long evenings in Trastevere, then take the first-class train north to Florence. In about an hour and a half you swap ancient ruins for Renaissance palaces, the Uffizi and Brunelleschi's dome. The two cities make a natural pair for a first trip to Italy.
You fly into Rome and home from Florence or Pisa, so there is no going back on yourself. Both hotels are central four-star boutique properties with breakfast, and private transfers take you between each hotel and the station. Florence is also a good base for a day in Siena, San Gimignano or the Chianti hills.
2 stops · 7 nights
Colosseum, Vatican, Trastevere
Duomo, Uffizi, Ponte Vecchio
Priced with these hotels or similar. Want a different hotel? Your Travel Designer will re-price it for you.
Four nights gives you time to see ancient Rome, the Vatican and the Baroque squares at an easy pace. Book the Vatican Museums and the Colosseum in advance, and leave evenings free for dinner in Trastevere or Monti.
Florence is compact enough to walk everywhere. Climb the Duomo, see Michelangelo's David at the Accademia and the Botticellis in the Uffizi, then cross the Ponte Vecchio to the Oltrarno for artisan workshops and quieter trattorias.
Guide prices per person, two sharing, with flights from London.
Prices checked October 2026. Prices change daily; your Travel Designer confirms today's live price before you book. Business class and regional airports on request.
Best time to go: April to June and September to October bring warm days and fewer crowds than midsummer. July and August are hot and busy; November to March is quieter and better value, with cooler weather.
A suggested plan. Change anything.
Fly from London to Rome Fiumicino, about 2½ hours, and transfer to your hotel. Take an evening stroll to the Trevi Fountain and the Spanish Steps.
See the Colosseum, Roman Forum and Palatine Hill, spend a morning in the Vatican Museums and St Peter's, and visit the Pantheon and Piazza Navona.
Transfer to Termini for the first-class train to Florence, about 90 minutes, then on to your hotel. Spend the afternoon around the Duomo and Piazza della Signoria.
Visit the Uffizi and the Accademia, cross the Ponte Vecchio and watch the sunset from Piazzale Michelangelo. A day trip to Siena or Chianti is easy to add.
Transfer to Florence airport, or Pisa, about 90 minutes away, for your flight back to the UK.
Same idea, different mix.
Live prices for a week with flights, updated daily. Pick one and we'll add the other stops.
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No hotels match. Airport, month and budget only apply to hotels with a price today, so try clearing those.
High-speed trains take about 1½ hours from Roma Termini to Firenze Santa Maria Novella, with departures most hours of the day.
Yes, we strongly recommend it. Timed tickets for the Vatican Museums, the Colosseum, the Uffizi and the Accademia often sell out, especially from spring to autumn.
Yes. Several UK airports have direct flights to Rome and to Pisa, though Florence's own airport has fewer UK routes. We will suggest the best pairing for your airport.
Yes. Venice is about 2¼ hours from Florence by high-speed train, and you can fly home from Venice instead.
Change the hotels, the nights or the order, or add a third stop. A Travel Designer replies within a few hours.
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