12 Oct 2026
Twin share
Incl. flights
Not sold tour only on this date
£4,789pp
Flights from London
Escorted tour
Chile, Argentina & Brazil with Flights: Andes, Iguazú & Rio – 14 Days
Santiago, the Andes crossing, Mendoza, Buenos Aires, Iguazú Falls and Rio, with flights from London.
14 days
From £4,789 incl. flights
Tour overview
This 14-day escorted tour crosses South America from the Pacific to the Atlantic, with return flights from London, internal flights and transfers all included. A holiday director travels with the group throughout, with local guides in each city. You stay in four- and five-star hotels, including the Hilton on Copacabana beach in Rio, with breakfast daily and a farewell dinner at a Brazilian churrascaria. Porterage is included.
After the overnight flight, you begin in Santiago, set beneath the Andes, with an afternoon city tour and a free day, perhaps for a vineyard visit. Then comes one of the great road journeys of the continent: over the Andes and across the border into Argentina, with views of Aconcagua, the highest mountain in the Americas, on the way to Mendoza, the wine capital at the foot of the mountains. A guided tour introduces the leafy city, with the afternoon free for its wineries.
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A flight takes you to Buenos Aires for three nights, with a city tour of the Plaza de Mayo, the colourful houses of La Boca and Recoleta Cemetery, resting place of Eva Perón. Free days allow for the Tigre delta by riverboat, a tango show or a day trip across the River Plate to Colonia del Sacramento in Uruguay.
At Iguazú Falls you stay two nights on the Argentine side and spend a full day in the national park, riding the jungle train and walking the upper and lower trails to the thundering Devil's Throat. The tour ends with two nights in Rio de Janeiro, with time for Sugarloaf Mountain, Christ the Redeemer and the beaches of Copacabana and Ipanema, and a farewell dinner before the flight home.
The pace mixes guided touring with free time, so you can choose how much to see. Optional excursions with your holiday director include a vineyard visit near Santiago, a riverboat trip on the Tigre delta and a day trip to Uruguay, while Rio offers Sugarloaf Mountain and Christ the Redeemer. Internal flights connect the longer legs, saving days of travel, and porterage is included, so you never have to carry your bags.
The physical rating is medium, with some early starts and walking at Iguazú. This tour suits travellers who want South America's great sights in comfort, with flights and hotels arranged.
Trip highlights
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A road journey over the Andes past Aconcagua (Day 4)
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Mendoza, Argentina's wine capital (Day 5)
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Buenos Aires
La Boca, Recoleta and Plaza de Mayo (Day 6)
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A full day at Iguazú Falls and the Devil's Throat (Day 10)
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Two nights on Copacabana beach in Rio (Days 11–12)
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Return flights from London and all internal flights
Your route
6 stops from Santiago to Rio de Janeiro
- Santiago Days 1–3
- Mendoza Days 4–5
- Buenos Aires Days 6–8
- Iguazú Falls Days 9–10
- Devil's Throat Day 10
- Rio de Janeiro Days 11–14
Why choose this tour
Flights from London, internal flights, four- and five-star hotels and a holiday director all included. Crosses the Andes by road rather than flying, for one of South America's great journeys.
Best suited to
- First-time visitors to South America
- Travellers who want flights and hotels arranged
- Couples and solo travellers who like comfort and company
- Anyone keen to see Iguazú and Rio
Day-by-day itinerary
14 days from London, United Kingdom to London, United Kingdom
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Day 1 · London Fly to Santiago
Fly overnight from London to Santiago, Chile's capital, via São Paulo.
- Hotel
- Overnight flight
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Day 2 · Santiago Santiago
Arrive in Santiago and transfer to your hotel for two nights. An afternoon tour shows you the city beneath the Andes, from its colonial heart to its hilltop viewpoints.
- Hotel
- Hotel Director Vitacura or similar
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Day 3 · Santiago Santiago at leisure
A free day to explore Santiago, or join an optional trip to a vineyard and the coast with your holiday director.
- Hotel
- Hotel Director Vitacura or similar
- Meals
- Breakfast
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Day 4 · Andes, Aconcagua, Mendoza Over the Andes to Mendoza
Travel by road over the Andes and across the border into Argentina, with views of Aconcagua, the highest peak in the Americas, on the way to Mendoza.
- Hotel
- Diplomatic Hotel Mendoza or similar
- Meals
- Breakfast
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Day 5 · Mendoza Mendoza
A guided tour of Mendoza, a leafy city of plazas at the foot of the Andes, with the afternoon free, perhaps for a wine tasting at one of the region's bodegas.
- Hotel
- Diplomatic Hotel Mendoza or similar
- Meals
- Breakfast
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Day 6 · Buenos Aires, La Boca, Recoleta Fly to Buenos Aires
Fly to Buenos Aires for three nights. An afternoon tour visits the Plaza de Mayo, the colourful district of La Boca and Recoleta Cemetery, where Eva Perón is buried.
- Hotel
- Hotel Libertador or similar
- Meals
- Breakfast
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Day 7 · Tigre Delta Buenos Aires at leisure
A free day, or take an optional riverboat trip through the waterways of the Tigre and Paraná delta.
- Hotel
- Hotel Libertador or similar
- Meals
- Breakfast
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Day 8 · Buenos Aires, Colonia del Sacramento Buenos Aires at leisure
Explore Buenos Aires at your own pace, or cross the River Plate to the old smugglers' town of Colonia del Sacramento in Uruguay.
- Hotel
- Hotel Libertador or similar
- Meals
- Breakfast
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Day 9 · Iguazú Falls Fly to Iguazú
Fly to Iguazú and settle into your hotel on the Argentine side of the falls for two nights.
- Hotel
- Panoramic Grand Hotel or similar
- Meals
- Breakfast
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Day 10 · Iguazú National Park, Devil's Throat Iguazú Falls
Spend a full day in Iguazú National Park, riding the jungle train and walking the upper and lower trails to the Devil's Throat, where the river plunges into a vast chasm.
- Hotel
- Panoramic Grand Hotel or similar
- Meals
- Breakfast
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Day 11 · Rio de Janeiro Fly to Rio de Janeiro
Fly to Rio de Janeiro and check in to your hotel on Copacabana beach.
- Hotel
- Hilton Copacabana or similar
- Meals
- Breakfast
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Day 12 · Sugarloaf Mountain, Copacabana Rio de Janeiro
Explore Rio, set beneath Sugarloaf Mountain, perhaps visiting Christ the Redeemer or the beaches of Copacabana and Ipanema. In the evening, enjoy a farewell dinner at a Brazilian churrascaria.
- Hotel
- Hilton Copacabana or similar
- Meals
- Breakfast, Dinner
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Day 13 · Rio de Janeiro Fly home
Time for a last look at Rio before your transfer to the airport and overnight flight to the UK via São Paulo.
- Hotel
- Overnight flight
- Meals
- Breakfast
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Day 14 · London Arrive in the UK
Arrive back in the UK, and the tour comes to an end.
Where you stay
- Santiago (2 nights) Hotel Director Vitacura or similar
- Mendoza (2 nights) Diplomatic Hotel Mendoza or similar
- Buenos Aires (3 nights) Hotel Libertador or similar
- Iguazú Falls (2 nights) Panoramic Grand Hotel or similar
- Rio de Janeiro (2 nights) Hilton Copacabana or similar
Hotel names are indicative and may be replaced with a property of similar standard and location.
What's included
Included
- Flights return from London, plus Mendoza to Buenos Aires, Buenos Aires to Iguazú and Iguazú to Rio
- Accommodation 11 nights in four- and five-star hotels
- Meals 11 breakfasts and a farewell dinner at a churrascaria
- Transport the road journey over the Andes and all transfers, with porterage
- Guided visits Santiago, Mendoza, Buenos Aires and a full day at Iguazú Falls
- Holiday director and local guides throughout
Not included
- Travel insurance
- Visas or entry requirements, where needed
- Meals not listed
- Optional excursions, such as Sugarloaf Mountain or a tango show
- Tips and personal spending
This trip might not be for you if…
Honest disclaimer — please read
- You want a small group — groups can be up to 35
- You want to fly from a regional airport — flights are from London
- You want most meals included — breakfasts and one dinner
- You want to see Patagonia — this tour covers the north
Good to know
In pictures
Departures & prices
From £4,789 per person, including flights. 8 upcoming departures.
Flights from London.
23 Nov 2026
Twin share
Incl. flights
Not sold tour only on this date
£4,789pp
Flights from London
08 Mar 2027
Twin share
Incl. flights
Not sold tour only on this date
£4,799pp
Flights from London
20 Sep 2027
Twin share
Incl. flights
Not sold tour only on this date
£4,799pp
Flights from London
22 Nov 2027
Twin share
Incl. flights
Not sold tour only on this date
£4,849pp
Flights from London
06 Mar 2028
Twin share
Incl. flights
Not sold tour only on this date
£4,959pp
Flights from London
18 Sep 2028
Twin share
Incl. flights
Not sold tour only on this date
£4,959pp
Flights from London
13 Nov 2028
Twin share
Incl. flights
Not sold tour only on this date
£5,009pp
Flights from London
Frequently asked questions
How do I book this tour?
Tap any "Enquire" button on the page and one of our travel specialists will be in touch within 24 hours (often same day). We'll confirm availability on your preferred date, run through anything you need to know, and only ask for the deposit once you've decided.
What financial protection do I get?
Every Travelisto booking is 100% financially protected. Your money is held in a ring-fenced Trust account until you return from your trip, and we are members of the Protected Trust Services scheme (PTS 6035). Most tours also include ATOL protection where flights are part of the package.
Are flights included?
Yes. Return flights from London, internal flights from Mendoza to Buenos Aires, Buenos Aires to Iguazú and Iguazú to Rio, and all transfers are included.
How do we cross the Andes?
By road from Santiago to Mendoza, a spectacular day's drive through the mountains and across the Chile–Argentina border, with views of Aconcagua.
Which side of Iguazú Falls do we visit?
The Argentine side, with a full day in the national park, including the jungle train and the walk to the Devil's Throat.
What meals are included?
11 breakfasts and a farewell dinner at a churrascaria in Rio. Other meals are at your own expense.
How many people travel together?
Between 15 and 35 travellers, with a holiday director and local guides.
Do I need visas?
UK passport holders do not currently need visas for Chile, Argentina or Brazil for short tourist stays. Check the latest rules before you travel.
Can you tailor the trip?
Yes — every escorted tour can be modified into a private tailor-made version with your own dates, adjusted pace, upgraded hotels and add-on extensions. Tell us what you'd like changed when you enquire and we'll quote it both ways so you can compare.
What if my flight is delayed or cancelled?
If your international flight is part of your booking through us, we re-book at no cost. If you've booked flights separately, the tour's local team holds your transfer slot until you arrive. We strongly recommend a comprehensive travel insurance policy that includes delay and cancellation cover.
ATOL protected
100% financially protected in a Trust bank account
PTS 6035
4.7 on Trustpilot
Tailor-made option
Not quite the right fit? Make it tailor-made.
If this group tour doesn't match your ideal trip, our specialists will turn it into a private tailor-made journey — your own dates, your own pace, upgraded hotels where you want them, and the parts you don't love swapped out. Same destinations, just rebuilt around you.
Contact us for a tailor-made version of this itinerary