Sometimes a holiday is about doing less, beautifully. The Mediterranean’s best spa hotels combine sea views and sunshine with treatments, thermal suites and wellness programmes that send you home genuinely rested.
Here are thirteen five-star spa hotels our guests rate most highly, from a 4,000 m² spa in Turkey to a lakeside wellness retreat on Lake Garda.
You’ll find on this page
- Quick verdicts and a comparison table of every hotel
- Thirteen five-star spa hotels
- How to get the most from a spa break
- Answers to the questions we’re asked most
- Live prices with flights and transfers in the search box at the end of the page
At a glance: compare the hotels
| Hotel | Where | Stars | Board | TripAdvisor | Adults only |
|---|---|---|---|---|---|
| Maxx Royal Kemer Resort | Kemer, Antalya | 5★ | All Inclusive Plus | 5/5 | No |
| Casaly Hotel & Spa | Argostoli, Kefalonia | 5★ | Bed and Breakfast | 5/5 | No |
| Villa Fiorella Art Hotel | Massa Lubrense, Sorrento & the Amalfi Coast | 5★ | Bed and Breakfast | 4.9/5 | No |
| Mazzaro Sea Palace | Taormina Mare, Sicily | 5★ | Bed and Breakfast | 4.9/5 | No |
| Andronis Concept Wellness Resort | Imerovigli, Santorini | 5★ | Bed and Breakfast | 4.9/5 | No |
| Amarande Hotel | Ayia Napa, Ayia Napa & Protaras | 5★ | Bed and Breakfast, Full Board, Half Board | 4.9/5 | No |
| Hotel Es Princep | Palma City, Balearic Islands | 5★ | Bed and Breakfast | 4.9/5 | No |
| Finca Ratxo Retreat Melia Collection | Puigpunyent, Majorca | 5★ | Bed and Breakfast, Half Board | 4.9/5 | No |
| Atrium Palace Thalasso Spa Resort & Villas | Kalathos, Rhodes | 5★ | All Inclusive Plus, Bed and Breakfast, Half Board | 4.8/5 | No |
| Lido Palace | Riva, Lake Garda | 5★ | Bed and Breakfast | 4.8/5 | No |
| Ikos Oceania | Nea Moudania, Halkidiki | 5★ | All Inclusive Plus | 4.8/5 | No |
| Regent Porto Montenegro | Tivat (Tivat Airport), Montenegro (Tivat Airport) | 5★ | Bed and Breakfast, Half Board | 4.8/5 | No |
| Palace Elisabeth Hvar | Hvar Island (Hvar Town), Split & the Dalmatian Coast | 5★ | Bed and Breakfast | 4.8/5 | No |
Star ratings are official; TripAdvisor scores were correct when we last checked and can change. Board options vary by room and date.
Quick verdicts
Our top picks
1. Maxx Royal Kemer Resort
- Kemer, Antalya
- 5-star
- All Inclusive Plus
- TripAdvisor 5/5
Maxx Royal Kemer’s heavenly 4,000 m² spa is one of the largest in the region, paired with superb dining and villas with private pools.
Best for: The ultimate spa resort
2. Casaly Hotel & Spa
- Argostoli, Kefalonia
- 5-star
- Bed and Breakfast
- TripAdvisor 5/5
Casaly Hotel & Spa in Argostoli, Kefalonia, is an adults-only property that is perfect for spa lovers, with a perfect score from guests.
Best for: Intimate, adults-only spa
3. Villa Fiorella Art Hotel
- Massa Lubrense, Sorrento & the Amalfi Coast
- 5-star
- Bed and Breakfast
- TripAdvisor 4.9/5
Villa Fiorella Art Hotel in Massa Lubrense, near Sorrento, is a boutique spa hotel with an infinity pool.
Best for: Amalfi Coast calm
4. Mazzaro Sea Palace
- Taormina Mare, Sicily
- 5-star
- Bed and Breakfast
- TripAdvisor 4.9/5
Mazzaro Sea Palace in Taormina has a sensational spa, a stunning beachfront location and suites with private pools.
Best for: Sicilian glamour
5. Andronis Concept Wellness Resort
- Imerovigli, Santorini
- 5-star
- Bed and Breakfast
- TripAdvisor 4.9/5
Andronis Concept Wellness Resort in Santorini is perfect for spa lovers, with private-pool suites and caldera views.
Best for: Wellness with a view
6. Amarande Hotel
- Ayia Napa, Ayia Napa & Protaras
- 5-star
- Full Board
- TripAdvisor 4.9/5
Amarande in Ayia Napa has relaxing indoor and outdoor pools and a sensational spa, perfect for adults.
Best for: Year-round Cyprus spa
7. Hotel Es Princep
- Palma City, Balearic Islands
- 5-star
- Bed and Breakfast
- TripAdvisor 4.9/5
Hotel Es Princep in Palma combines a fantastic spa with a rooftop infinity pool and modern, luxurious design in the old town.
Best for: A city spa break
8. Finca Ratxo Retreat Melia Collection
- Puigpunyent, Majorca
- 5-star
- Half Board
- TripAdvisor 4.9/5
Finca Ratxo in Majorca’s hills is perfect for spa lovers, with traditional luxury and an inviting outdoor pool.
Best for: Rural Majorca
9. Atrium Palace Thalasso Spa Resort & Villas
- Kalathos, Rhodes
- 5-star
- All Inclusive Plus
- TripAdvisor 4.8/5
Atrium Palace Thalasso Spa Resort on Rhodes is perfect for spa lovers, with thalassotherapy, superb dining and private-pool rooms.
Best for: Thalasso therapy
10. Lido Palace
- Riva, Lake Garda
- 5-star
- Bed and Breakfast
- TripAdvisor 4.8/5
A member of The Leading Hotels of the World, Lido Palace in Riva del Garda is perfect for spa lovers, with incredible panoramic lake views.
Best for: Lake Garda luxury
11. Ikos Oceania
- Nea Moudania, Halkidiki
- 5-star
- All Inclusive Plus
- TripAdvisor 4.8/5
Ikos Oceania in Halkidiki has a luxurious spa and gourmet cuisine on All Inclusive Plus.
Best for: All-inclusive with a great spa
12. Regent Porto Montenegro
- Tivat (Tivat Airport), Montenegro (Tivat Airport)
- 5-star
- Half Board
- TripAdvisor 4.8/5
Regent Porto Montenegro in Tivat is perfect for spa lovers, with exceptional service and stunning décor on the Bay of Kotor.
Best for: Superyacht glamour
13. Palace Elisabeth Hvar
- Hvar Island (Hvar Town), Split & the Dalmatian Coast
- 5-star
- Bed and Breakfast
- TripAdvisor 4.8/5
Palace Elisabeth on the harbour front of Hvar Town has a regal style and is perfect for honeymoons.
Best for: Croatian island elegance
How to get the most from a spa break
Book treatments when you book your holiday, as popular slots fill quickly. Arrive early for thermal suites. Choose half board or bed and breakfast at city and boutique spa hotels, so you can enjoy local restaurants too. Spring and autumn are perfect for spa breaks, with fewer crowds and comfortable temperatures.
How we chose these hotels
We sell 2785 hotels across Europe and beyond. To build this list we started with the five-star hotels whose spas our guests and selling points rate most highly, then read what our guests say: every hotel here scores highly on TripAdvisor. We picked no more than one or two per destination so you can compare places as well as hotels, and we only include hotels you can book with us today as an ATOL-protected package with flights and transfers. Prices change daily, so use the search box at the end of this page for live availability, or ask a Travel Designer for a tailored shortlist.
Frequently asked questions
Which Mediterranean hotel has the biggest spa?
Maxx Royal Kemer in Turkey, with a 4,000 m² spa.
Are spa treatments included?
Usually not, though some hotels include spa access. Ask a Travel Designer about packages.
What is thalassotherapy?
Spa treatments using seawater and marine products, offered at hotels such as Atrium Palace Thalasso on Rhodes.
When is the best time for a spa holiday?
Spring and autumn, when the weather is comfortable and hotels are quieter.
Find your spa escape
Search live prices with flights and transfers, all ATOL protected, or ask a Travel Designer to add spa treatments to your booking.
Keep planning
- Greece holidays
- Italy holidays
- Turkey holidays
- Best honeymoon hotels in Europe
- Best adults-only luxury hotels in the Mediterranean
- Best hotels on Lake Garda
- Best hotels in Madeira
- Best spa hotels in Turkey
Updated October 2026. Hotels can be booked as ATOL-protected packages with flights and transfers through Travelisto.
