Gemcitabine Used As First And Second-line Chemotherapy Of Lung CancerGemcitabine could be used as first and second-line chemotherapy of advanced non-small cell lung cancer. "[The aim] of this study was to estimate efficacy of gemcitabine in first and the second-line chemotherapy for patients with advanced non-small cell lung cancer (stage III and TV). In first-line chemotherapy, 120 patients were treated with different chemotherapy regimens," scientists in Croatia reported. "Fifty-nine patients were treated with gemcitabine/cisplatin (PG), 41 with cisplatin / etoposide (PE) and 20 with mitomycin / ifosamide / cisplatin (MIC). Forty patients, unsuccessfully treated with PE and MIC in first-line therapy were treated with PG (24 pts) and with best supportive care (BSC) (16 pts)," explained B. Cucevic and...
Alfacell Forms New Thoracic Cancer Advisory Board Bloomfield, NJ - Alfacell Corporation (Nasdaq: ACEL) today announced the formation of a Thoracic Cancer Advisory Board to support the Company’s strategic focus on developing novel ribonuclease (RNase) therapies for the treatment of diseases such as mesothelioma and non-small cell lung cancer (NSCLC). The Thoracic Cancer Advisory Board will work in coordination with the Company’s prestigious [...]
Elevated Protein Levels Linked to Mesothelioma Scientists at New York University School of Medicine and Wayne State University have found a molecule that reveals the early stages of pleural mesothelioma, a chest cancer caused by asbestos. The finding opens the way to a blood test for the disease, according to a new study published in the Oct. 13 issue of The New England Journal of Medicine. An estimated 7.5 million workers in the United States have been exposed to asbestos and, according to government statistics, it remains a hazard to some 1.3 million workers in construction and building maintenance.er Registry, either had no or low occupational exposure to asbestos. ......
Tumor Size Related to Cancer Spread(UPI via COMTEX) -- New York City scientists say smaller lung tumors appear to be less likely to have spread than larger tumors among patients with asymptomatic lung cancer. The finding by Dr. Claudia Henschke of the New York Presbyterian Hospital-Weill Cornell Medical Center and colleagues suggests early screening may be useful in detecting cancers that are still curable. Writing in the Archives of Internal Medicine, the researchers say although tumor size has been linked to cancer prognosis in patients with symptoms, the relationship between tumor size, metastasis and prognosis in asymptomatic individuals has been unclear. The scientists screened 28,689 men and women for lung cancer at 38 institutions worldwide b...
Chromosome Arms That Correlate With Colon Cancer Metastases IdentifiedChromosome arms that correlate with occurrences of colon cancer metastases were identified. According to a study from France, "The decision to use chemotherapy in the treatment of colon cancer patients depends on the risk of developing metastases, as estimated by clinicopathological staging combining body imaging and pathological findings. The aim of this study was to identify all chromosome arms that, when allelotyped, correlate with the metastatic process, add prognostic information to pathology, and are of relevance for predicting metachronous metastases." "A 5-year follow-up survey enrolled 401 MSS (microsatellite stable) colon cancer patients who were divided into 3 groups. Staging was performed with and without imaging data (cal...
Jury Finds Chrysotile Asbestos Causes Rare Peritoneal Mesothelioma A jury awarded over $1.9 million to a 71-year-old retired sheet metal worker, Genaro Garcia, who developed peritoneal mesothelioma from his prior on-the-job exposure to asbestos (Genaro Garcia and Dalia Garcia v. Duro Dyne Corporation, SF Superior Court, #418098). Peritoneal mesothelioma is an aggressive form of cancer that first attacks the membranes lining the stomach. This fatal disease is almost always caused by asbestos exposure.......